Computational characterization and expression profile of MTP1 gene associated with zinc homeostasis across dicot plant species

This study characterizes different MTP1 (metal tolerance protein)/ZAT (zinc transporter) homologs involved in zinc (Zn) homeostasis plants. BLAST analysis of AtMTP1 protein against 15 plant species showed 21 homologs. These generally contain ~400 residues, six transmembrane helices and cation transporter activity (GO:0008324), which can be utilized predicting Zn uptake mechanisms. genes having 1 exon are located on chromosomes 2, 7, 14. Motifs conserved sequences 41–50 residues belonging to the efflux family, may help target binding sites transcription factors. Further, shows close similarities with Glycine max Medicago trunculata. Interactome suggests association cadmium/zinc-transporting ATPase ZIP metal ion transporter. The network is predominantly connected (heavy HMA2; heavy 3, HMA3; 4, HMA4), (MTP11), C3 (AT4G58060). Genevestigator predicts high expression potential apical root during senescence, seedling, bolting stages an 11 co-expressed genes, mainly linked estradiol toxicity heat stress. Besides, possess N-glyco motifs physicochemical properties. similarity interactions gene other suggest that plants associated regulation genes. findings advance our understanding further develop capable maintaining under adverse conditions.